Thursday, October 9, 2014

Ensuring polymorphic purity in drugs

Reliable batch-to-batch formation is crucial for crystalline, active pharmaceutical ingredients as two different polymorphs of the same drug may function very differently in the body. Scientists now report that the surface chemistry of modified glass substrates can influence the nucleation and formation of specific polymorphs of the drug, carbamazepine, within a certain concentration range of supersaturated solutions.

from Geochemistry News -- ScienceDaily


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